2021年7月至今,中国农业大学 教授 博士生导师
2019年7月-2021年6月,中国科学院遗传与发育生物学研究所,博士后
2013年9月-2019年6月,中国科学院遗传与发育生物学研究所,博士
2009年9月-2013年6月,西北农林科技大学,本科
植物精准基因组编辑技术的研发和应用;植物合成生物学技术的研究;小麦重要性状的分子设计与育种。
国家重点研发计划青年科学家项目,2021-2026,主持
国家自然科学基金青年项目,2021-2023,主持
博士后创新人才支持计划,2019-2021,主持
博士后面上一等资助,2019-2021,主持
国家自然科学基金面上项目,2020-2023,参加
入选2019年度未来女科学家计划
1. Zong Y#, Liu Y#, Xue C#, Li B, Li X, Wang Y, Li J, Liu G, Huang X, Cao X, Gao C (2022) An engineered prime editor with enhanced editing efficiency in plants. Nature Biotechnology, doi: 10.1038/s41587-022-01254-w.
2. Guo M#, Wang Q#, Zong Y#, Nian J, Li H, Li J, Wang T, Gao C, Zuo J (2021) Genetic manipulations of TaARE1 boost nitrogen utilization and grain yield in wheat. Journal of Genetics and Genomics, 48(10):950-953.
3. Lin Q#, Jin S#, Zong Y#, Yu H#, Zhu Z, Liu G, Kou W, Wang Y, Qiu, J.L, Li J, Gao C (2021) High-efficiency prime editing with optimized, paired pegRNAs in plants. Nature Biotechnology, 39(8):923-927.
4. Wang S#, Zong Y#, Lin Q#, Zhang H#, Chai Z, Zhang D, Chen K, Qiu JL, Gao C (2020) Precise, predictable multi-nucleotide deletions in rice and wheat using APOBEC-Cas9. Nature Biotechnology, 8(12):1460-1465.
5. Lin Q#, Zong Y#, Xue C#, Wang S, Jin S, Zhu Z, Wang Y, Anzalone AV, Raguram A, Doman JL, Liu DR, Gao C (2020) Prime genome editing in rice and wheat. Nature Biotechnology, 38(5):582-585. (Recommended in F1000Prime).
6. Li C, Zong Y, Jin S, Zhu H, Lin D, Li S, Qiu JL, Wang Y, Gao C (2020) SWISS: multiplexed orthogonal genome editing in plants with a Cas9 nickase and engineered CRISPR RNA scaffolds. Genome Biology, 21(1):141.
7. Li C#, Zhang R#, Meng X#, Chen S, Zong Y, Lu C, Qiu JL, Chen YH, Li J, Gao C (2020) Targeted, random mutagenesis of plant genes with dual cytosine and adenine base editors. Nature Biotechnology, 38(7):875-882.
8. 宗媛,高彩霞. 碱基编辑系统研究进展. 遗传, 2019, 41(9): 777-800.
9. Jin S#, Zong Y#, Gao Q#, Zhu Z, Wang Y, Qin P, Liang C, Wang D, Qiu J, Zhang F, Gao C (2019) Cytosine, but not adenine, base editors induce genome-wide off-target mutations in rice. Science, 364, 292-295.
10. Zhang R#, Liu J#, Chai Z, Chen S, Bai Y, Zong Y, Chen K, Li J, Jiang L, and Gao C (2019) Generation of herbicide tolerance traits and a new selectable marker in wheat using base editing. Nature Plants, 5, 480-485.
11. Zong Y#, Song Q#, Li C, Jin S, Zhang D, Wang Y, Qiu JL, Gao C (2018) Efficient C-to-T base editing in plants using a fusion of nCas9 and human APOBEC3A. Nature Biotechnology, 36, 950-953.
12. Li C#, Zong Y#, Wang Y#, Jin S, Zhang D, Song Q, Zhang R, Gao C (2018) Expanded base editing in rice and wheat using a Cas9-adenosine deaminase fusion. Genome Biology, 19, 59.
13. Zong Y#, Wang Y#, Li C, Zhang R, Chen K, Ran Y, Qiu J, Wang D, Gao C (2017) Precise base editing in rice, wheat and maize with a Cas9-cytidine deaminase fusion, Nature Biotechnology, 35, 438. (Recommended in F1000Prime).
14. Wang Y, Zong Y, and Gao C (2017). Targeted mutagenesis in hexaploid bread wheat using the TALEN and CRISPR/Cas systems. Methods in Molecular Biology, 1679, 169-185.
15. Zhang Y#, Liang Z#, Zong Y#, Wang Y, Liu J, Chen K, Qiu J, Gao C (2016) Efficient and transgene-free genome editing in wheat through transient expression of CRISPR/Cas9 DNA or RNA. Nature Communications, 7, 12617.
16. Liang Z, Zong Y, and Gao C (2016). An efficient targeted mutagenesis system using CRISPR/Cas in monocotyledons. Current Protocols in Plant Biology, 1, 329-344.
17. Li J#, Meng X#, Zong Y, Chen K, Zhang H, Liu J, Li J, Gao C (2016) Gene replacements and insertions in rice by intron targeting using CRISPR/Cas9. Nature Plants, 2 (10), 16139.